2B4 抗体
(4 references)Quick Overview for 2B4 抗体 (ABIN2689111)
抗原
See all 2B4 (CD244) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with a 66 kDa single chain transmembrane glycoprotein. 2B4 belong to the immunoglobulin superfamily of proteins and is structurally related to CD2-like molecules. It was originally identified in the mouse as a non-MHC-restricted cytotoxicity mediator present on NK cells and CD8+ T cells. In humans, 2B4 is expressed on NK cells, CD8+ T cells, monocytes and basophils, suggesting a broader role for 2B4 in leukocyte activation and possibly a role of immunomodulation in other receptor-ligand interactions to enhance leukocyte activation. 2B4 has been clustered as CD244 in the VIIth HLDA workshop. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of CD244 (2-69) reactivity on peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.
BD Pharmingen™ Purified Mouse Anti-Human CD244 - Purified - Clone 2-69 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG2a kappa
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anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 20-221) antibody
CD244 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (N-Term) antibodyCD244 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) antibodyCD244 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM69 unconjugated Recombinant Antibody
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 151-250) antibodyCD244 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (pTyr271) antibodyCD244 适用: 人 WB, FACS, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 26-212) antibodyCD244 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-224) antibodyCD244 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-224) antibodyCD244 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) antibodyCD244 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) antibodyCD244 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal 2B4-69 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "2B4 functions as a co-receptor in human NK cell activation." in: European journal of immunology, Vol. 30, Issue 3, pp. 787-93, (2000) (PubMed).
: "Activating interactions in human NK cell recognition: the role of 2B4-CD48." in: European journal of immunology, Vol. 29, Issue 5, pp. 1676-83, (1999) (PubMed).
: "Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 6981-5, (1999) (PubMed).
: "Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 10, pp. 5328-37, (1993) (PubMed).
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: "2B4 functions as a co-receptor in human NK cell activation." in: European journal of immunology, Vol. 30, Issue 3, pp. 787-93, (2000) (PubMed).
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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别名
- CD244
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背景
- Synonyms: 2B4
抗原
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